Sam Saunders and Toumani Diagagoru featured for Brentford’s development side in a match against Tottenham on Tuesday afternoon.Winger Saunders has been out for three weeks with a knee problem, while midfielder Diagagoru has not featured this term after suffering a knee injury during pre-season.Striker David Clarkson, recently signed on loan from Bristol City, also played against a Spurs team that included William Gallas and former Bees loanee John Bostock.AdChoices广告Saunders played the first half and Clarkson an hour, while Diagagoru lasted the entire 90 minutes.Brentford won the game 2-1 with goals from Harry Forrester and Mike Grella.
The new discovery from China dates back 130 million years on the evolutionary timeline.A few days ago, we reported the discovery of melanin from a fossil bird found in the Liaoning Province, China, that was dated at 120 million years (early Cretaceous) in the evolutionary scheme. Now, another discovery from the Jehol strata of China is said to be 10 million years older: 130 million years.The discovery by Pan et al., “Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous bird Eoconfuciusornis,” is published in the Proceedings of the National Academy of Sciences. Once again, Mary Schweitzer from North Carolina State is listed as a co-author. A laymen’s writeup is on Science Daily, taken from an NC State press release. Schweitzer has been in the thick of reports about soft tissue in dinosaur bones and other dinosaur-era fossils.New research from North Carolina State University, the Chinese Academy of Sciences and Linyi University has found evidence of original keratin and melanosome preservation in a 130-million-year-old Eoconfuciusornis specimen. The work extends the timeframe in which original molecules may preserve, and demonstrates the ability to distinguish between ancient microstructures in fossils.Eoconfuciusornis, crow-sized primitive birds that lived in what is now China around 130 million years ago, are the earliest birds to have a keratinous beak and no teeth, like modern birds. Previous studies argued that the feathers of these and other ancient birds and dinosaurs preserved small, round structures interpreted to be melanosomes – pigment-containing organelles that, along with other pigments, give feathers their color.Electron micrographs and gold-tipped antibodies that bind to melanin were used to make the identification. Another technique clinched the identity of original protein:Finally, they mapped copper and sulfur to these feathers at high resolution. Sulfur was broadly distributed, reflecting its presence in both keratin and melanin molecules in modern feathers. However copper, which is only found in modern melanosomes, and not part of keratin, was only observed in the fossil melanosomes. These findings both support the identity of the melanosomes and indicate that there was no mixing or leaching during decomposition and fossilization.The paper describes how they avoided contamination. The antibody tests confirm that the proteinaceous is original. In modern feathers, melanosomes are “always surrounded by and embedded in keratin.” The scientists demonstrate this was true in the fossil as well.Our work represents the oldest ultrastructural and immunological recognition of avian beta-keratin from an Early Cretaceous (∼130-Ma) bird. We apply immunogold to identify protein epitopes at high resolution, by localizing antibody–antigen complexes to specific fossil ultrastructures. Retention of original keratinous proteins in the matrix surrounding electron-opaque microbodies supports their assignment as melanosomes and adds to the criteria employable to distinguish melanosomes from microbial bodies. Our work sheds new light on molecular preservation within normally labile tissues preserved in fossils.Confuciusornis was clearly a strong flyer. Artist renditions of Eoconfuciusornis (“dawn Confuciusornis“) show it also equipped for flying.So how did “normally labile tissues” last for 130 million years? The researches speculate about needle-like crystals of calcium they found on the fossil:These Ca-concentrated needle-shaped structures are absent in extant feathers. Thus, we hypothesize that precipitation of calcium, possibly mediated by microbes during the fossilization process, facilitated ultrastructural and molecular preservation of the feathers by stabilizing them at the molecular level before they could completely degrade. It has long been known that the association with mineral substrates greatly enhances the preservation potential of biomolecules. Furthermore, it has been proposed that calcium may incorporate into molecular fragments, conferring stability, and that this process may be microbially mediated. Because the surrounding sediments of this Eoconfuciusornis specimen consist mainly of Al silicates, with little or no calcium detected, the source of the calcium observed in these feathers remains unknown.So while the presence of calcium crystals could “possibly” stabilize the proteins (for support, the team references a 1999 paper by Schweitzer), they don’t know where it came from. They propose another stabilizing influence:Another factor that may contribute to the unique biomaterial properties of feathers is the epidermal differentiation cysteine-rich protein. This molecule has the same gene structure as beta-keratins, and is coexpressed with them at certain stages of development in most keratinized tissues of living birds. However, it is only in feathers that this protein continues to be detected throughout life. The greatly elevated cysteine levels in this protein facilitate intramolecular cross-linking, and contribute to the stability and resistance of feathers to degradation. Further molecular recovery of ancient feather materials may allow direct testing of these hypotheses. It should be possible to measure degradation rates of feather keratin and melanosomes due to the presence of calcium or cysteine. But if either of these processes are so efficient, it would seem original feather material should be common in bird fossils, and we should find preserved fossils over a wide range, from recent kills all the way back. 130 million years is a long, long time to have to account for the preservation of original protein material.Creationists are winning this case. Why? (1) Evolutionists did not predict this, and (2) they are scrambling to explain it away. You just heard them call these proteins “normally labile tissues.” Labile means easily altered, broken down or degraded. But the team hollered, It tastes like chicken!Indeed, if both microbodies and matrix are preserved, tests can be conducted to chemically characterize the composition of each. If these bodies are melanosomes, they should be contained within a keratinous matrix; if they are microbial in origin, this matrix should consist of exopolymeric substances secreted by the microbes and subsequently mineralized. To distinguish between these alternative hypotheses, we applied multiple methods, well-established for molecular and chemical characterization of modern materials, to chicken (Gallus gallus) feathers and to preserved feathers of a new specimen of the bird Eoconfuciusornis [Shandong Tianyu Museum of Nature (STM) 7-144] (Pygostylia: Confuciusornithiformes) (Fig. 1A) from the 130-Ma Protopteryx horizon of the Huajiying Formation in Fengning, northern Hebei, China. Our results are consistent with the retention of original organic components derived from both keratin and melanin, thus supporting a melanosome origin for these ancient microstructures.(Visited 50 times, 1 visits today)FacebookTwitterPinterestSave分享0
Sicelo Shiceka heads up the Department of Cooperative Governance and Traditional Affairs, formerly Department of Provincial and Local Government. Arts and Culture: Lulu XingwanaCommunications: Siphiwe NyandaCorrectional Services: Nosiviwe Mapisa-NqakulaDefence and Military Veterans: Lindiwe SisuluHealth: Aaron MotsoalediHome Affairs: Nkosazana Dlamini-ZumaJustice and Constitutional Development: Jeff RadebeLabour: Membathisi MdladlanaPublic Enterprises: Barbara HoganPublic Works: Geoff DoidgeScience and Technology: Naledi PandorSocial Development: Edna MolewaSport and Recreation: Makhenkesi StofileTransport: Sbusiso Ndebele The second function within the Presidency will be overseen by Collins Chabane. The Department of Education has also been split, with Angie Motshekga now Minister of Basic Education and Blade Nzimande becoming Minister of Higher Education and Training. Zuma stressed that while civil servants would not lose their jobs as a result of the changes, an era of hard work had begun, and that public workers who did their work diligently and efficiently had nothing to worry about. The Department of Minerals and Energy has been split into two separate departments, with Susan Shabangu appointed Minister of Mining and Dipuo Peters becoming Minister of Energy. “We have also created a monitoring and evaluation competency in the Presidency, to monitor and evaluate the performance of government in all three spheres,” Zuma said. “There will therefore be two Ministers in the Presidency, one responsible for the NPC, and the other for monitoring and evaluation as well as administration in the Presidency.” National Planning Commission Would you like to use this article in your publication or on your website? See: Using SAinfo material The commission will be responsible for strategic planning for the country to ensure one national plan to which all spheres of government will adhere, paving the way for a more comprehensive approach to socio-economic development in the country. Policymaking, implementation focus “We have since the launch of the ANC manifesto indicated the type of new administration we envisaged in terms of size, shape and political focus,” Zuma said in Pretoria on Sunday. “It should be a structure which would enable us to effectively implement our policies.” Water Affairs merges with Environmental Affairs in the Department of Water and Environmental Affairs under Buyelwa Sonjica, a new-look Department of Agriculture, Fisheries and Forestry is headed by Tina Joemat-Pettersson, while Marthinus van Schalkwyk leads the Department of Tourism. Former South African Revenue Service (Sars) commissioner Pravin Gordhan has been appointed the country’s new Minister of Finance. Sars has been praised as one of the best functioning government institutions since Gordhan took over in 1999. South African President Jacob Zuma has unveiled a new administrative team comprising 34 ministers, with a Cabinet and government departments reorganised in a bid to achieve “visible and tangible socio-economic development” within the next five years. The Department of Foreign Affairs has changed to the Department of International Relations and Cooperation, with Maite Nkoana-Mashabane as minister. Following extensive research on international models on how governments in other parts of the world plan and monitor performance, it was decided to establish a National Planning Commission (NPC), headed by former Finance Minister Trevor Manuel, which will be based in the Presidency. A new Department of Economic Development, headed by Ebrahim Patel, has been established to focus on economic policymaking. The implementation function, however, remains with the Department of Trade and Industry under Rob Davies. Other appointments, in departments that remain unchanged, are: Unchanged ministries There is a new Department of Rural Development and Land Affairs, headed by Gugile Nkwinti, as well as a Department of Human Settlements (formerly Housing), headed by Tokyo Sexwale. Noluthando Mayende-Sibiya leads the new Department for Women, Youth, Children and People with Disability, created to emphasise the need for equity and access to development opportunities for vulnerable groups in South African society. 11 May 2009 “With these objectives in mind, I am confident that the new structure of government will enable the state machinery to speed up service delivery.” ‘Era of hard work’ “We reiterate that we will not tolerate laziness and incompetence, and that we will emphasise excellence and achievement from the Cabinet and the public service,” Zuma said. SAinfo reporter Departmental changes The Department of Safety and Security is now the Department of Policing, with Nathi Mthethwa remaining as minister, while the Department of Intelligence is now the Department of State Security, with Siyabonga Cwele in charge.
IT Trends of the Future That Are Worth Paying A… For Self-Driving Systems, Infrastructure and In… Google’s Waymo has unveiled the first images of its self-driving minivan, a customized version of the Fiat Chrysler Pacifica hybrid that has been in development for six months.The minivan has been outfitted with all of Google’s latest self-driving technology, including an array of updated sensors, a more powerful computer system, and software updates.See Also: Former head of Google car project to launch his own self-driving rival“As we get fully self-driving cars ready for the road, we’ll need more types of vehicles to refine and test our advanced driving software,” said Waymo CEO, John Krafcik. “With this great new minivan on the road in our test markets, we’ll learn how people of all ages, shapes, and group sizes experience our fully self-driving technology.”To make all of the extra baggage fit, Waymo engineers made design changes to the Chrysler Pacifica hybrid, showing that Google’s self-driving division is capable of working and customizing automotive hardware, if the need arises.Waymo test-drives have begunWaymo has already run a variety of tests on the minivan at its own test track in California and Fiat’s Chelsea Proving Grounds in Michigan and Arizona Proving Grounds in Yucca, AZ, including over 200 hours of extreme weather testing.Krafcik has not given a specific deployment date in his Medium post, but said he was “looking forward” to having the minivans on public roads by 2017. The 100 minivans will join Google’s other self-driving vehicles in Kirkland, WA, Mountain View, CA, metro Phoenix, AZ, and Austin, TX.Waymo has not confirmed if it will build its own self-driving vehicles, or even if it really just seeking to be sold off by Google. The success of the partnership with Fiat suggests Google doesn’t need to spend billions acquiring hardware talent, though that may change once Apple, Tesla, and Uber divulge their full plans. 5 Ways IoT can Help to Reduce Automatic Vehicle… Related Posts David Curry Break the Mold with Real-World Logistics AI and… Tags:#autonomous cars#Chrysler Pacifica#driverless cars#Fiat#Google#minivan#Self-Driving#Waymo
Author: Christian Maino Vieytes, B.S. Nutritional Sciences, University of Maryland, College Park, M.S. Candidate, Division of Nutritional Sciences, University of Illinois at Urbana-ChampaignFor a long time, it has been common knowledge that stress kills. Scientific knowledge has come to the forefront while attempting to answer how stress mediates this effect. Indeed, there are now enormous research efforts examining the relationships and mechanisms by which psychological stress mediates decreased longevity. Population-based research has demonstrated that those that bare higher amounts of psychological stress also have a higher risk of death as compared to their more jovial counterparts1.What do we mean by stress? Stress is routinely dichotomized into two varieties: eustress and distress2. Eustress can be thought of as “good” kind stress and is the kind of stress that motivates you to engage, for instance, in the activities one enjoys pursuing. Distress, on the other hand, is the type of stress associated with feeling overwhelmed or fatigued. Namely among the variables impacted by high amounts of distress are physical activity, sleep, and diet/nutrition. By understanding how psychological distress influences this three-legged stool we get a better sense of how we can address them. Thankfully, there has been much research examining this matter.Lack of sleep stemming from significant stress can be problematic because it also affects the other two legs of the three-legged stool we have identified (diet and physical activity). Studies have demonstrated that a lack of sleep can cause an increase in the amount of calories we consume on a given day3. Negative mood stemming from psychological stress and lack of sleep may also be responsible for evening-time overeating patterns4. The way that decreased sleep may impact eating patterns is by its effect on our hunger hormones5. Lack of sleep may also contribute to a lack of engagement in physical activity, which then leads to poorer outcomes and a higher risk of stress and chronic illness6.Importantly, however, is that the other two legs of the stool (diet and physical activity) also exert effects on sleep quality. A 2017 study done on 5,062 women found that those women who exercised more tended to be protected from insomnia7. In a meta-analysis review of multiple studies looking at the effects of exercise on sleep, researchers found that regular exercise imparts benefit on and impacts total sleep time, sleep efficiency, sleep onset latency, and on sleep quality8.The question of how diet can affect sleep is also an interesting one that has gained attention. In a cohort study of 3,816 men that examined eating and sleeping patterns in men, researchers from Penn State and Harvard Universities found that those that overconsumed calories had low intakes of fruits and vegetables, and had the greatest intakes of sodium and trans-fat also tended to have the highest likelihood of experiencing insomnia9. Several studies have suggested that consuming a diet that is more Mediterranean in nature may be a way of combatting insomnia 10,11. Research focusing on specific dietary nutrients that may be associated with sleep quality and insomnia have narrowed in on the importance of getting adequate amounts of vitamin D12 (which we obtain primarily from the being outside and exposed to sunlight!).The 3-legged stool framework examined and explored here was only modestly addressed. The extent of the research on the effects of combatting stress through a comprehensive lifestyle and wellness regimen that focuses primarily on sleep, diet, and physical activity, is massive. Nevertheless, the following big-picture conclusion is substantiated by the research reported as well as novel and ongoing research: following a plan that focuses on consuming a diet that revolves primarily around whole-foods, limits the consumption of high-fat and processed foods, and incorporates a daily physical activity regimen is likely to, in some way, impart benefit to the psychological distress you face in your life13.References:Okely JA, Weiss A, Gale CR. The interaction between stress and positive affect in predicting mortality. J Psychosom Res. 2017;100:53-60. doi:10.1016/j.jpsychores.2017.07.005Le Fevre M, Matheny J, Kolt GS. Eustress, distress, and interpretation in occupational stress. Journal of Managerial Psychology. 2003;18(7):726-744. doi:10.1108/02683940310502412McHill AW, Wright KP. Role of sleep and circadian disruption on energy expenditure and in metabolic predisposition to human obesity and metabolic disease. Obes Rev. 2017;18 Suppl 1:15-24. doi:10.1111/obr.12503Liu Y, Song Y, Koopmann J, Wang M, Chang C-HD, Shi J. Eating your feelings? Testing a model of employees’ work-related stressors, sleep quality, and unhealthy eating. J Appl Psychol. 2017;102(8):1237-1258. doi:10.1037/apl0000209Stern JH, Grant AS, Thomson CA, et al. Short sleep duration is associated with decreased serum leptin, increased energy intake and decreased diet quality in postmenopausal women. Obesity (Silver Spring). 2014;22(5):E55-61. doi:10.1002/oby.20683Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic diseases. Compr Physiol. 2012;2(2):1143-1211. doi:10.1002/cphy.c110025Spörndly-Nees S, Åsenlöf P, Lindberg E. High or increasing levels of physical activity protect women from future insomnia. Sleep Med. 2017;32:22-27. doi:10.1016/j.sleep.2016.03.017Kredlow MA, Capozzoli MC, Hearon BA, Calkins AW, Otto MW. The effects of physical activity on sleep: a meta-analytic review. J Behav Med. 2015;38(3):427-449. doi:10.1007/s10865-015-9617-6Cheng FW, Li Y, Winkelman JW, Hu FB, Rimm EB, Gao X. Probable insomnia is associated with future total energy intake and diet quality in men. Am J Clin Nutr. 2016;104(2):462-469. doi:10.3945/ajcn.116.131060St-Onge M-P, Mikic A, Pietrolungo CE. Effects of Diet on Sleep Quality. Adv Nutr. 2016;7(5):938-949. doi:10.3945/an.116.012336Jaussent I, Dauvilliers Y, Ancelin M-L, et al. Insomnia symptoms in older adults: associated factors and gender differences. Am J Geriatr Psychiatry. 2011;19(1):88-97. doi:10.1097/JGP.0b013e3181e049b6Grandner MA, Jackson N, Gerstner JR, Knutson KL. Sleep symptoms associated with intake of specific dietary nutrients. J Sleep Res. 2014;23(1):22-34. doi:10.1111/jsr.12084Soltani H, Keim NL, Laugero KD. Diet Quality for Sodium and Vegetables Mediate Effects of Whole Food Diets on 8-Week Changes in Stress Load. Nutrients. 2018;10(11). doi:10.3390/nu10111606
In the fourth edition of The Graduates, austouch.com.au caught up with former Queensland Secondary Schools Touch (QSST) player, Nathan Norford, who played for the North Queensland Tropical Cyclones at the 2010 X-Blades National Youth Championships. After two years playing for QSST, Nathan Norford’s final National Youth Championships was a chance to play for his permit, North Queensland, for the first time at the NYC level.And it turned out to be an impressive performance from the Tropical Cyclones 18’s Boys team, making it to the semi finals of the event. Norford hopes that his experience and leadership at this year’s NYC helps the side for years to come and hopes he can continue to help the side in other roles in the future. “Further down the track I’d love to coach these boys and mentor them. I’ve got my little brother playing in the side and he played really well and all the young boys, it’s a good chance for them to play on a bigger stage,” he said. Norford had his chance to play against QSST on day one of the NYC, and says that he was ‘a bit nervous’ but enjoyed playing against his former team. “We played them early in the tournament, we came out and matched them for close to 10 to 15 minutes and then Queensland kept their same intensity and we couldn’t match it for the whole game I guess,” Norford said. “It’s the first time I’ve ever played for Cyclones, everyone likes to play for their region. At the same time, you’ve got a little bit of rivalry between the New South Wales and the Queensland teams. It’s a little bit of pressure on yourself to stand up to that.”Norford has plenty of fond memories of his time at the National Youth Championships over the past three years and says that he is ‘pretty disappointed’ that it has all come to an end, but knows there is plenty to look forward to in the future. “You always love coming away to these championships, and it’s a good way to test out your ability but there’s still 20’s and there’s still Open’s, so there’s a lot to look forward to.”“Probably the biggest thing I enjoy about Youth Champs is playing a good standard of Touch. Week in, week out we probably don’t get that as much in Townsville or North Queensland compared to the southern areas. (I also enjoy) meeting new people, seeing some many people, and you’re all here for the same passion.”
Juventus forward Ronaldo: I’m not obsessed with individual awardsby Carlos Volcano10 months agoSend to a friendShare the loveJuventus forward Cristiano Ronaldo denies being obsessed with individual awards.Ronaldo says he doesn’t live to break records and leaving the national team was his decision, although he will return in 2019.”I’m not obsessed with individual prizes,” said Ronaldo. “The important thing is helping the team, always, and therefore the rest arrives naturally.”I don’t hide that I’m happy when I win but it’s not the end of the world if it can’t happen.”He added that “leaving the national team for a while after the Russia World Cup was the best decision” although he said he would be ready to come back in 2019. About the authorCarlos VolcanoShare the loveHave your say
Juventus boss Sarri admits Man Utd target Mandzukic not training with squadby Paul Vegas7 days agoSend to a friendShare the loveJuventus boss Maurizio Sarri admits Mario Mandzukic is not training with his first team squad as he prepares for a January exit.The Croatian striker has been tipped to join Manchester United when the transfer window re-opens and bolster Ole Gunnar Solskjaer’s attacking options. “Mandzukic is not training with us, in agreement with the club,” the Juve head coach told a news conference on Friday.”If the agreement changes, I am open to everything.”Sporting director Fabio Paratici confirmed talks with Mandzukic over his future this week.”With Mandzukic, we chose a quiet time for him to leave but a move to Qatar [in the summer] did not materialise so he stayed with us,” Paratici said.”Now we will talk to him and see what happens in January. We are evaluating, he is also evaluating. We need maximum calm, he is a great player.”It has been an added value in recent years, we must thank him. If he considers it appropriate to leave, we will satisfy him, otherwise he will consider other solutions.” TagsTransfersAbout the authorPaul VegasShare the loveHave your say
The keel laying ceremony of Silver Moon, the second of three new ultra-luxury Muse cruise ships that Fincantieri is building for Silversea Cruises, took place at the Ancona yard on February 14.Silver Moon will be a sister ship of Silver Muse, which took the sea in 2017, and of Silver Dawn due to delivery in 2021.The 40,700 gross ton cruise ship, which will have a capacity to accommodate 596 passengers on board, is expected to enter the ship owner’s fleet in 2020.Silver Moon, which will be the 10th ship in Silversea’s fleet, was assigned the ‘Green star 3 Design’ voluntary notations, meaning that the unit would be designed, built and equipped in order to prevent air and water pollution.Image Courtesy: Fincantieri
REGINA – Premier Brad Wall says the organization representing Saskatchewan First Nations has requested financial compensation be tied to an apology to victims of the ’60s Scoop.Wall won’t say how much the Federation of Sovereign Indigenous Nations is asking for in compensation.“We wanted to make a decision around the apology,” he said Wednesday.“It was offered informally, and now we’ve been working for a very long time to accommodate a more formal apology at the location and the time of the choosing of the Metis Nation and the FSIN.“I respect the fact that they’ve now added an ask for money, a financial commitment from the government, but we haven’t made the decision.”Wall announced two years ago that an apology would be coming for the policy that removed Indigenous children from their homes and placed them with non-Indigenous families — a practice that stripped the children of their language, culture and traditions.He said at the time that the province did not intend to offer cash to the victims.The FSIN could not immediately be reached for comment Wednesday.Saskatchewan radio station MBC reported last month that federation Chief Bobby Cameron said he would be seeking the same settlement — or at least half of — a federal promise of up to $800 million for victims.Wall said that’s not something the government’s going to be doing.“You a can have an apology without money,” Wall said. “We still would like to go ahead with it.”Wall has said he hopes the apology can take place before he retires in January.Manitoba became the first province to apologize to Indigenous adoptees in 2015.